Choline compound that crosses the blood-brain barrier efficiently and is metabolised to free choline, a building block for acetylcholine; studied for cognitive performance and, at higher doses, acute power output in training.
Subjective feeling of mental cloudiness — difficulty thinking clearly, concentrating, or remembering.
Also known as: Alpha-glycerylphosphorylcholine
Every published result for this pair, extracted and audited.
Research volume over time for Alpha-GPC × brain fog. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-AnalysisBonvicini M, et al. · Nutrients · 2023PMID 36678257 ↗02Application of Citicoline in Neurological Disorders: A Systematic ReviewJasielski P, et al. · Nutrients · 2020PMID 33053828 ↗03Use of Citicoline in Attention-Deficit/Hyperactivity Disorder: A Pilot StudyHübner IB, et al. · Clinical neuropharmacology · 2024PMID 38976279 ↗04Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy MenKerksick CM · Nutrients · 2024PMID 39683633 ↗05Effects of branched chain amino acids, l-citrulline, and alpha-glycerylphosphorylcholine supplementation on exercise performance in trained cyclists: a randomized crossover trialBe the first to share what you noticed with Alpha-GPC for brain fog. How we calculate this.