Alpha-GPC for Memory

Choline compound that crosses the blood-brain barrier efficiently and is metabolised to free choline, a building block for acetylcholine; studied for cognitive performance and, at higher doses, acute power output in training.

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On this pageOverview Evidence Community outcomes Related

Why Alpha-GPC for Memory?

The connection

Short-term memory, recall, and age-related memory decline.

Also known as: Alpha-glycerylphosphorylcholine

Evidence analytics

Alpha-GPC × Memory: at a glance

Every published result for this pair, extracted and audited.

These charts group published studies by what they reported and how they were run — green marks studies that reported a benefit for this pairing. Tiers run from pooled analyses of many trials (strongest) to one-off observational reports.

What the evidence shows

Direction of reported outcomes for Alpha-GPC in memory.

Benefit

Evidence quality mix

Study designs behind these findings.

Randomised trial

Studies

Reviews & meta-analyses

RCT findings

120

Participants (where reported)

Study results, as reported by the publications

Every measured outcome, one row per finding - numbers exactly as reported.

Study	Design	n	Duration	Outcome measured	Reported result	Direction
PMID 1916007 1991	Randomised trial	120	90 days	Psychometric performance in vascular dementia	reported qualitatively	Benefit
PMID 2071257 1991	Randomised trial	Thirty-two	ten day	Attention and memory after scopolamine	reported qualitatively	Benefit

← Zoom out: all evidence for Alpha-GPC Zoom out: compare compounds for Memory →

Peer-reviewed research

Alpha-GPC × Memory: the evidence base

Hand-selected PubMed studies, linked to the originals.

6studies referenced

4journals

2020–2026publication range

Ordered by strength of evidence, then result direction.

01Comparative effects of Bacopa monnieri and Ginkgo biloba on cognitive functions: A systematic review and network meta-analysisTiemtad P, et al. · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2026PMID 41678913 ↗02Efficiency of Different Supplements in Alleviating Symptoms of ADHD with or Without the Use of Stimulants: A Systematic ReviewAl Shahab S, et al. · Nutrients · 2025PMID 40362791 ↗03Plant-derived nootropics and human cognition: A systematic reviewLorca C, et al. · Critical reviews in food science and nutrition · 2023PMID 34978226 ↗04Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-AnalysisBonvicini M, et al. · Nutrients · 2023PMID 36678257 ↗

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Important: This page reflects observational, aggregate-only community reporting and independent published research. It is not medical advice, and it does not claim any compound treats, cures, or is effective for any condition. Always consult a qualified healthcare professional before starting, stopping, or changing any supplement or treatment.