Full-spectrum ashwagandha root extract standardised for withanolide content using a low-temperature aqueous extraction process; the most heavily trialled ashwagandha formulation for cortisol reduction and stress resilience.
Generalized anxiety, social anxiety, panic disorder, and related conditions. Affects 1 in 6 people in the UK.
Also known as: KSM-66 Ashwagandha
Every published result for this pair, extracted and audited.
Research volume over time for Ashwagandha KSM-66 × anxiety. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a (1)H-magnetic resonance spectroscopy meta-analysisMaddock RJ, et al. · Molecular psychiatry · 2025PMID 40913113 ↗02Effects of Different Cannabinoid Formulations on Anxiety-Related Disorders, and Tourette Syndrome: A Systematic Review and Meta-AnalysisRaminelli AO, et al. · Cannabis and cannabinoid research · 2025PMID 40956670 ↗03Do "testosterone boosters" really increase serum total testosterone? A systematic reviewMorgado A, et al. · International journal of impotence research · 2024PMID 37697053 ↗04Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic ReviewMohammed SYM, et al. · Pain management nursing : official journal of the American Society of Pain Management Nurses · 2024PMID 37953193 ↗Be the first to share what you noticed with Ashwagandha KSM-66 for anxiety. How we calculate this.