Adaptogenic root herb whose withanolide compounds are thought to blunt HPA-axis cortisol release; clinical trials link standardised extracts to reduced perceived stress and anxiety scores.
Persistent low frustration tolerance, quick temper, or emotional reactivity that affects relationships.
Also known as: Withania somnifera
Every published result for this pair, extracted and audited.
Research volume over time for Ashwagandha × irritability / anger. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Effects of ashwagandha (Withania somnifera) on mental health in adults: A systematic review and dose-response meta-analysis of randomized controlled trialsAlsanie SA, et al. · Complementary therapies in medicine · 2026PMID 41644067 ↗02Safety and efficacy of Withania somnifera for anxiety and insomnia: Systematic review and meta-analysisFatima K, et al. · Human psychopharmacology · 2024PMID 39083548 ↗03Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysisArumugam V, et al. · Explore (New York, N.Y.) · 2024PMID 39348746 ↗04Plant-derived nootropics and human cognition: A systematic reviewLorca C, et al. · Critical reviews in food science and nutrition · 2023PMID 34978226 ↗Be the first to share what you noticed with Ashwagandha for irritability / anger. How we calculate this.