Isoquinoline plant alkaloid that activates AMP-activated protein kinase (AMPK); trials show blood-glucose-lowering effects in type 2 diabetes approaching those of metformin, though GI side effects are common.
Non-alcoholic fatty liver disease. Fat accumulation in the liver, often linked to insulin resistance and obesity.
Also known as: Berberine HCl
Every published result for this pair, extracted and audited.
Research volume over time for Berberine × fatty liver (nafld). Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Adjunctive berberine for schizophrenia with metabolic syndrome: a systematic review and meta-analysisXie K, et al. · Frontiers in psychiatry · 2026PMID 42433212 ↗02Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-AnalysisMiao R, et al. · Phytotherapy research : PTR · 2025PMID 40439602 ↗03Efficacy and safety of berberine on the components of metabolic syndrome: a systematic review and meta-analysis of randomized placebo-controlled trialsLiu D, et al. · Frontiers in pharmacology · 2025PMID 40740996 ↗04The Effect of Berberine Supplementation on Glycemic Control and Inflammatory Biomarkers in Metabolic Disorders: An Umbrella Meta-analysis of Randomized Controlled TrialsBe the first to share what you noticed with Berberine for fatty liver (nafld). How we calculate this.