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Fat-soluble compound essential to mitochondrial ATP production and antioxidant defence; levels decline with age and statin use, so supplementation is studied for statin-associated muscle symptoms and cardiovascular support.
Cardiovascular health — blood pressure, cholesterol, heart function, and circulation.
Also known as: CoQ10, Ubiquinone, Ubiquinol
Every published result for this pair, extracted and audited.
These charts group published studies by what they reported and how they were run — green marks studies that reported a benefit for this pairing. Tiers run from pooled analyses of many trials (strongest) to one-off observational reports.
Direction of reported outcomes for Coenzyme Q10 in heart health.
Study designs behind these findings.
Every measured outcome, one row per finding - numbers exactly as reported.
| Study | Design | n | Duration | Outcome measured | Reported result | Direction |
|---|---|---|---|---|---|---|
| PMID 35608922 2021 | Meta-analysis | 568 | - | adverse events | 0.70 RR (95% CI 0.45 to 1.10) | Unclear |
| PMID 35608922 2021 | Meta-analysis | 420 | - | all-cause mortality | 0.58 RR (95% CI 0.35 to 0.95) | Benefit |
| PMID 35608922 2021 | Meta-analysis | 91 | - | exercise capacity | 48.23 MD (95% CI -24.75 to 121.20) | Unclear |
| PMID 35608922 2021 | Meta-analysis | 1061 | - | hospitalisation related to heart failure | 0.62 RR (95% CI 0.49 to 0.78) | Benefit |
| PMID 35608922 2021 | Meta-analysis | 650 | - | left ventricular ejection fraction | 1.77 MD (95% CI 0.09 to 3.44) | Benefit |
| PMID 35608922 2021 | Meta-analysis | 420 | - | myocardial infarction | 1.62 RR (95% CI 0.27 to 9.59) | Unclear |
| PMID 35608922 2021 | Meta-analysis | 420 | - | stroke | 0.18 RR (95% CI 0.02 to 1.48) | Unclear |
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Taurine supplementation as a therapeutic strategy for cellular senescence and chronic inflammation in long COVID: a systematic review and meta-analysisWang K, et al. · BMC infectious diseases · 2026PMID 41803812 ↗02Dietary Supplementation for Fatigue Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)-A Systematic ReviewDorczok MC, et al. · Nutrients · 2025PMID 39940333 ↗03Energy Drinks as the Legal Cocaine? A Comparative Review of Cardiac Physiopathological and Histopathological PatternsGhamlouch A, et al. · Cardiovascular toxicology · 2025PMID 41266869 ↗04Coenzyme Q10 supplementation in rheumatic diseases: A systematic reviewFreire de Carvalho J, et al. · Clinical nutrition ESPEN · 2024PMID 38220408 ↗Be the first to share what you noticed with Coenzyme Q10 for heart health. How we calculate this.