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Sugar alcohol, not a true vitamin, involved in insulin signal transduction and cell membrane structure; myo-inositol is well studied for improving insulin sensitivity and ovulation in PCOS, and for reducing panic and anxiety symptoms.
Generalized anxiety, social anxiety, panic disorder, and related conditions. Affects 1 in 6 people in the UK.
Also known as: Myo-inositol, D-Chiro-inositol
Every published result for this pair, extracted and audited.
These charts group published studies by what they reported and how they were run — green marks studies that reported a benefit for this pairing. Tiers run from pooled analyses of many trials (strongest) to one-off observational reports.
Direction of reported outcomes for Inositol in anxiety.
Study designs behind these findings.
Every measured outcome, one row per finding - numbers exactly as reported.
| Study | Design | n | Duration | Outcome measured | Reported result | Direction |
|---|---|---|---|---|---|---|
| PMID 24424706 2014 | Meta-analysis | - | - | Anxiety and obsessive-compulsive symptoms | reported qualitatively | No benefit |
| PMID 24424706 2014 | Meta-analysis | - | - | Depressive symptoms | reported qualitatively | No benefit |
| PMID 24424706 2014 | Meta-analysis | - | - | Treatment discontinuation | reported qualitatively | No benefit |
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Comparison of metformin with inositol versus metformin alone in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trialsKelly FA, et al. · Endocrine · 2025PMID 39331347 ↗02Transdiagnostic reduction in cortical choline-containing compounds in anxiety disorders: a (1)H-magnetic resonance spectroscopy meta-analysisMaddock RJ, et al. · Molecular psychiatry · 2025PMID 40913113 ↗03Effects of Different Cannabinoid Formulations on Anxiety-Related Disorders, and Tourette Syndrome: A Systematic Review and Meta-AnalysisRaminelli AO, et al. · Cannabis and cannabinoid research · 2025PMID 40956670 ↗04Effectiveness of Cannabidiol to Manage Chronic Pain: A Systematic ReviewMohammed SYM, et al. · Pain management nursing : official journal of the American Society of Pain Management Nurses · 2024Be the first to share what you noticed with Inositol for anxiety. How we calculate this.