Compound library
Understand what people are taking.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
Conditionally essential amino acid and substrate for nitric oxide synthase; oral supplementation has been studied for effects on vascular function, blood pressure and exercise performance.
3 of 14 results reported a benefit, from 3 published studies.
3 studies, including a review of trials
These are the figures the studies reported, not a prediction for any one person. Where several studies measured the same thing in the same unit, we show a simple average and say so. Every individual result is listed below.
See every resultCardiovascular health — blood pressure, cholesterol, heart function, and circulation.
Also known as: Arginine, L-Arginine Hydrochloride
Every published result for this pair, extracted and audited.
These charts group published studies by what they reported and how they were run — green marks studies that reported a benefit for this pairing. Tiers run from pooled analyses of many trials (strongest) to one-off observational reports.
Direction of reported outcomes for L-Arginine in heart health.
Study designs behind these findings.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Taurine supplementation as a therapeutic strategy for cellular senescence and chronic inflammation in long COVID: a systematic review and meta-analysisWang K, et al. · BMC infectious diseases · 2026PMID 41803812 ↗02Energy Drinks as the Legal Cocaine? A Comparative Review of Cardiac Physiopathological and Histopathological PatternsGhamlouch A, et al. · Cardiovascular toxicology · 2025PMID 41266869 ↗03Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysisQazi SU, et al. · Future cardiology · 2024PMID 39049769 ↗04Insights into the cardiovascular benefits of taurine: a systematic review and meta-analysisTzang CC, et al. · Nutrition journal · 2024PMID 39148075 ↗Be the first to share what you noticed with L-Arginine for heart health. Why counts start empty.
Every measured outcome, one row per finding - numbers exactly as reported.
| Study | Design | n | Duration | Outcome measured | Reported result | Direction |
|---|---|---|---|---|---|---|
| PMID 34967840 2022 | Meta-analysis | - | - | diastolic BP (DBP) | -2.64 mmHg (95% CI: -3.94, -1.40; P < 0.001) | Benefit |
| PMID 34967840 2022 | Meta-analysis | - | - | systolic BP (SBP) | -6.40 mmHg (95% CI: -8.74, -4.05; P < 0.001) | Benefit |
| PMID 39683461 2024 | Randomised trial | Thirty-two | - | Heart rate recovery (HRR) | reported qualitatively (p = 0.944) | No benefit |
| PMID 39683461 2024 | Randomised trial | Thirty-two | - | Mean arterial pressure (MAP) | reported qualitatively (p = 0.687) | No benefit |
| PMID 39683461 2024 | Randomised trial | Thirty-two | - | Pulse pressure (PP) | reported qualitatively (p = 0.929) | No benefit |
| PMID 39683461 2024 | Randomised trial | Thirty-two | - | Root mean square of successive differences in the RR interval (RMSSD30) of heart rate variability (HRV) | reported qualitatively (p = 0.562) | No benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | arterial pressure | reported qualitatively (p > 0.05) | No benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | forearm skin vascular conductance | reported qualitatively (p > 0.05) | No benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | heart rate | reported qualitatively (p > 0.05) | No benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | mean skin temperature | reported qualitatively (p > 0.05) | No benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | oxygen consumption | reported qualitatively (p > 0.05) | No benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | plasma L-ARG concentrations | +223 ± 80% | Benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | rectal temperature | reported qualitatively (p > 0.05) | No benefit |
| PMID 26563117 2016 | Randomised trial | Eight | 90 min | sweat loss | reported qualitatively (p > 0.05) | No benefit |