Organic sulphur compound providing a bioavailable sulphur source for collagen and keratin synthesis; studied for joint pain, exercise-induced muscle soreness, and allergy symptoms, usually alongside glucosamine.
Pain in the lower, mid, or upper back. Often muscular but can involve disc, nerve, or joint issues.
Also known as: MSM, Organic sulphur
Every published result for this pair, extracted and audited.
Research volume over time for MSM (Methylsulfonylmethane) × back pain. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Efficacy and Safety of Anti-nerve Growth Factor Monoclonal Antibodies in Managing Chronic Musculoskeletal Pain: A Systematic Review with Network Meta-analysisAbouelella A, et al. · Drugs · 2026PMID 41880116 ↗02Efficacy of dietary supplements for treating knee osteoarthritis: a systematic review and network meta-analysisDu P, et al. · Frontiers in nutrition · 2025PMID 40123938 ↗03A large meta-analysis identifies genes associated with anterior uveitisGelfman S, et al. · Nature communications · 2023PMID 37949852 ↗04Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritisBrien S, et al. · Osteoarthritis and cartilage · 2008PMID 18417375 ↗Be the first to share what you noticed with MSM (Methylsulfonylmethane) for back pain. How we calculate this.