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Water-soluble antioxidant vitamin and essential cofactor for collagen synthesis and non-haem iron absorption; supports immune cell function and skin integrity, and cannot be made by the human body.
Acute mountain sickness — headache, nausea, fatigue, and shortness of breath at high altitude.
Also known as: Ascorbic Acid
Every published result for this pair, extracted and audited.
Research volume over time for Vitamin C × altitude sickness. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Clinical benefits and risks of high-dose intravenous vitamin C: a systematic reviewAlangari A, et al. · Journal of medicine and life · 2026PMID 41815850 ↗02Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026Weiss SL, et al. · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026PMID 41869844 ↗03Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026Weiss SL, et al. · Intensive care medicine · 2026PMID 41870559 ↗04Granulomatous Reactions From Microneedling: A Systematic Review of the LiteratureFriedmann DP, et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025PMID 39584690 ↗Be the first to share what you noticed with Vitamin C for altitude sickness. How we calculate this.