Water-soluble antioxidant vitamin and essential cofactor for collagen synthesis and non-haem iron absorption; supports immune cell function and skin integrity, and cannot be made by the human body.
Recurring herpes simplex virus outbreaks causing blisters on lips or around the mouth.
Also known as: Ascorbic Acid
Every published result for this pair, extracted and audited.
Research volume over time for Vitamin C × cold sores. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Clinical benefits and risks of high-dose intravenous vitamin C: a systematic reviewAlangari A, et al. · Journal of medicine and life · 2026PMID 41815850 ↗02Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026Weiss SL, et al. · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026PMID 41869844 ↗03Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026Weiss SL, et al. · Intensive care medicine · 2026PMID 41870559 ↗04Granulomatous Reactions From Microneedling: A Systematic Review of the LiteratureFriedmann DP, et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025PMID 39584690 ↗Be the first to share what you noticed with Vitamin C for cold sores. How we calculate this.