Direct metabolic precursor to serotonin, derived from Griffonia simplicifolia seeds, bypassing the rate-limiting step in serotonin synthesis; must not be combined with SSRIs, MAOIs, or other serotonergic drugs due to serotonin syndrome risk.
Appetite control, fat loss support, metabolic rate, and healthy weight maintenance.
Also known as: 5-Hydroxytryptophan, Griffonia simplicifolia
Every published result for this pair, extracted and audited.
Research volume over time for 5-HTP × weight management. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Does green tea catechin enhance weight-loss effect of exercise training in overweight and obese individuals? a systematic review and meta-analysis of randomized trialsGholami F, et al. · Journal of the International Society of Sports Nutrition · 2024PMID 39350601 ↗02Non-pharmacological factors for hypertension management: a systematic review of international guidelinesManiero C, et al. · European journal of preventive cardiology · 2023PMID 35947982 ↗03Green tea promotes weight loss in women with polycystic ovary syndrome: Systematic review and meta-analysisColonetti L, et al. · Nutrition research (New York, N.Y.) · 2022PMID 35504067 ↗04Does tea extract supplementation benefit metabolic syndrome and obesity? A systematic review and meta-analysisLi X, et al. · Clinical nutrition (Edinburgh, Scotland) · 2020PMID 31174941 ↗Be the first to share what you noticed with 5-HTP for weight management. How we calculate this.