Full-spectrum ashwagandha root extract standardised for withanolide content using a low-temperature aqueous extraction process; the most heavily trialled ashwagandha formulation for cortisol reduction and stress resilience.
Chronic stress, burnout, high cortisol. Distinct from anxiety — stress is the response, anxiety is the reaction.
Also known as: KSM-66 Ashwagandha
Every published result for this pair, extracted and audited.
Research volume over time for Ashwagandha KSM-66 × stress. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Potential Bioactive Function of Microbial Metabolites as Inhibitors of Tyrosinase: A Systematic ReviewBarcenas-Giraldo S, et al. · International journal of molecular sciences · 2026PMID 41596661 ↗02Effects of ashwagandha (Withania somnifera) on mental health in adults: A systematic review and dose-response meta-analysis of randomized controlled trialsAlsanie SA, et al. · Complementary therapies in medicine · 2026PMID 41644067 ↗03Mechanism of Ganoderma lucidum polysaccharides in the mangement of diabetes and its complicationsXin Y, et al. · Frontiers in pharmacology · 2026PMID 42147328 ↗04Edible and Medicinal Fungi as Candidate Natural Antidepressants: Mechanisms and Nutritional ImplicationsGong P, et al. · Molecular nutrition & food research · 2025PMID 40289452 ↗Be the first to share what you noticed with Ashwagandha KSM-66 for stress. How we calculate this.