Glycosaminoglycan naturally present in skin, joint synovial fluid, and connective tissue, capable of binding many times its weight in water; oral and injectable forms are studied for skin hydration and joint lubrication.
Acne, ageing skin, elasticity, hydration, wound healing, and overall skin appearance.
Also known as: HA, Sodium hyaluronate
Every published result for this pair, extracted and audited.
Research volume over time for Hyaluronic Acid × skin health. Structured outcome extraction (direction, effect size) for this pair is in progress - the full analytics will appear here once audited.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Efficacy, Durability, and Safety of Collagen Biostimulators Based on Poly-L-Lactic Acid (PLLA) and Calcium Hydroxyapatite (CaHA) in the Face: A Systematic ReviewFerreira ACM, et al. · Aesthetic plastic surgery · 2026PMID 41184662 ↗02Granulomatous Reactions From Microneedling: A Systematic Review of the LiteratureFriedmann DP, et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025PMID 39584690 ↗03A meta-analysis and systematic review of the clinical efficacy and safety of platelet-rich plasma combined with hyaluronic acid (PRP + HA) versus PRP monotherapy for knee osteoarthritis (KOA)Du D, et al. · Journal of orthopaedic surgery and research · 2025PMID 39819683 ↗04Stem cell injections for osteoarthritis of the kneeWhittle SL, et al. · The Cochrane database of systematic reviews · 2025PMID 40169165 ↗Be the first to share what you noticed with Hyaluronic Acid for skin health. How we calculate this.