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About Skin Health — Physical Health.
Acne, ageing skin, elasticity, hydration, wound healing, and overall skin appearance.
Audited published research per compound. Drill into a pair for the breakdown.
Bar length counts published studies — green marks studies reporting at least one benefit, slate the other studies (no benefit, unclear or harm); labels read benefit studies / all studies.
◆ marks each compound's research score (0-100): how consistently published studies reported a benefit, weighted by study design. It summarises the research, not how well a compound will work for you.
Compounds with published trial evidence for this condition, ranked by strength of evidence. Each result is put in plain terms and comes from the study itself — open “Exact figures” for the published statistics, or follow the study link to read the paper.
| Compound | Evidence strength | What studies found |
|---|---|---|
| Vitamin CResearch score 33/100 · Mixed/Weak | 1 systematic review/meta-analysis — 1 study | 2/3 outcomes showed benefit
|
We publish community results for skin health only once at least 10 people have reported on the same compound — so no individual report is ever shown. Until then, here is the research side on its own.
Used something for skin health? Sharing how it went for you helps the next person — it is only ever published as part of a group of 10 or more.
Add your outcomeOpen the original papers, check their methods, and discuss what is relevant with a qualified professional.
Every study behind the numbers above is linked next to its result.
Ordered by strength of evidence, then result direction.
01Efficacy, Durability, and Safety of Collagen Biostimulators Based on Poly-L-Lactic Acid (PLLA) and Calcium Hydroxyapatite (CaHA) in the Face: A Systematic ReviewFerreira ACM, et al. · Aesthetic plastic surgery · 2026Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 41184662 ↗02Granulomatous Reactions From Microneedling: A Systematic Review of the LiteratureFriedmann DP, et al. · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 39584690 ↗03Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsMyung SK, et al. · The American journal of medicine · 2025Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 40324552 ↗04Effects of collagen-based supplements on skin's hydration and elasticity: A systematic review and meta-analysisDanessa G, et al. · Indian journal of dermatology, venereology and leprology · 2025Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
PMID 40826844 ↗05Skin Aging and Carotenoids: A Systematic Review of Their Multifaceted Protective MechanismsStanescu C, et al. · Nutrients · 2025These compounds appear in related research or traditional use. Their position is not a recommendation or ranking. Research scores summarise published studies only.
Systematic Review · matched via Skin Health · PubMed record (CORPUS-A)
Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.
Ordered by strength of evidence, then result direction.
Reduced by approximately 50%
Acne patients · Systematic review & meta-analysis · PMID 30697370 ↗Strong evidenceReduced02Skin elasticity and hydration — ImprovedImproved after 8+ weeks of hydrolysed collagen
Adults supplementing collagen · Systematic review · PMID 31253804 ↗Strong evidenceImprovedFigures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.