Compound library
Understand what people are taking.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
Browse medicines, supplements, herbs, and health foods. Each profile brings community reports and linked research into one clear view.
Polyphenol from grape skins and Japanese knotweed, famous for extending lifespan in yeast and mice. It has been tested in many human trials without convincing clinical benefit. Umbrella reviews rate its effects on blood sugar, cholesterol and blood pressure as trivial or very low certainty, and a meta-analysis of human brain and mood trials found the animal results are not replicated in people.
5 of 9 results reported a benefit, from 2 published studies.
2 studies, including a review of trials
An umbrella review pooling the earlier meta-analyses found no clear change in LDL cholesterol; one dose-response review reported a small fall.
These are the figures the studies reported, not a prediction for any one person. Where several studies measured the same thing in the same unit, we show a simple average and say so. Every individual result is listed below.
See every resultLDL, HDL, triglycerides, and lipid profile management.
Also known as: trans-Resveratrol
Every published result for this pair, extracted and audited.
These charts group published studies by what they reported and how they were run — green marks studies that reported a benefit for this pairing. Tiers run from pooled analyses of many trials (strongest) to one-off observational reports.
Direction of reported outcomes for Resveratrol in cholesterol.
Study designs behind these findings.
Hand-selected PubMed studies, linked to the originals.
Ordered by strength of evidence, then result direction.
01Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-AnalysisMiao R, et al. · Phytotherapy research : PTR · 2025PMID 40439602 ↗02Efficacy and safety of berberine on the components of metabolic syndrome: a systematic review and meta-analysis of randomized placebo-controlled trialsLiu D, et al. · Frontiers in pharmacology · 2025PMID 40740996 ↗03The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic reviewNie Q, et al. · Journal of translational medicine · 2024PMID 38429794 ↗04Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled TrialsBe the first to share what you noticed with Resveratrol for cholesterol. Why counts start empty.
Every measured outcome, one row per finding - numbers exactly as reported.
| Study | Design | n | Duration | Outcome measured | Reported result | Direction |
|---|---|---|---|---|---|---|
| PMID 39255906 2024 | Meta-analysis | - | - | high-density lipoprotein cholesterol (HDL-c) (standardised mean difference) | 0.00 (95% CI: -0.04, 0.05; p =0.92) | No benefit |
| PMID 39255906 2024 | Meta-analysis | - | - | Lipid profile (weighted mean difference analysis) | reported qualitatively | No benefit |
| PMID 39255906 2024 | Meta-analysis | - | - | low-density lipoprotein-cholesterol (LDL-c) (standardised mean difference) | -0.16 mg/dl (95% CI: -0.40, 0.07; p =0.17) | No benefit |
| PMID 39255906 2024 | Meta-analysis | - | - | serum triglyceride (TG) (standardised mean difference) | -0.14 mg/dl (95% CI: -0.24, -0.03; p = 0.001) | Benefit |
| PMID 39255906 2024 | Meta-analysis | - | - | total cholesterol (TC) (standardised mean difference) | -0.20 (95% CI: -0.31, -0.08; p= 0.001) | Benefit |
| PMID 36145131 2022 | Meta-analysis | - | - | high-density lipoprotein cholesterol (HDL-C) | reported qualitatively | No benefit |
| PMID 36145131 2022 | Meta-analysis | - | - | low-density lipoprotein cholesterol (LDL-C) | −5.69 (95%CI: −11.07, −0.31; p = 0.038) | Benefit |
| PMID 36145131 2022 | Meta-analysis | - | - | total cholesterol (TC) | −10.28 (95%CI: −13.79, −6.76; p < 0.001) | Benefit |
| PMID 36145131 2022 | Meta-analysis | - | - | triglyceride (TG) | reported qualitatively (95%CI: −12.37, −4.75; p < 0.001) | Benefit |