Cholesterol

About Cholesterol — Metabolic Health.

LDL, HDL, triglycerides, and lipid profile management.

3studies analysed

1compounds with evidence

Meta-analysisstrongest evidence

Where research is strongest

Berberine 62

2linked compounds

9linked studies

0published community reports

On this pageBy the numbers Community outcomes Research Compounds

Evidence analytics

Where the evidence is concentrated.

Audited published research per compound. Drill into a pair for the breakdown.

Bar length counts published studies — green marks studies reporting at least one benefit, slate the other studies (no benefit, unclear or harm); labels read benefit studies / all studies.

Studies reporting a benefit
Other studies
◆ Research score (0-100)

◆ marks each compound's research score (0-100): how consistently published studies reported a benefit, weighted by study design. It summarises the research, not how well a compound will work for you.

Degree of benefit: what studies found for Cholesterol

Compounds with published trial evidence for this condition, ranked by strength of evidence. Each result is put in plain terms and comes from the study itself — open “Exact figures” for the published statistics, or follow the study link to read the paper.

Compound	Evidence strength	What studies found
BerberineResearch score 62/100 · Moderate	1 systematic review/meta-analysis + 2 randomised trials — 3 studies	19/22 outcomes showed benefit HDL cholesterol (overall) — 'good' cholesterol0.06 mmol/L higherbenefit2023 study ↗ Exact figures 0.06 mmol/L (95% CI 0.00 to 0.11) n=1471 · 4 to 24 weeks · PMID 36941490 HDL cholesterol (women) — 'good' cholesterol0.11 mmol/L higherbenefit2023 study ↗ Exact figures 0.11 mmol/L (95% CI 0.09 to 0.13) · 4 to 24 weeks · PMID 36941490

Community outcomes

No community reports published yet.

We publish community results for cholesterol only once at least 10 people have reported on the same compound — so no individual report is ever shown. Until then, here is the research side on its own.

Berberine
Research saysResearch score 62/100 · Moderate3 of 3 studies reported at least one benefit
People reportNot published yet — needs 10 or more reports

Used something for cholesterol? Sharing how it went for you helps the next person — it is only ever published as part of a group of 10 or more.

Add your outcome

Peer-reviewed research

Keep evidence in the room.

Open the original papers, check their methods, and discuss what is relevant with a qualified professional.

Every study behind the numbers above is linked next to its result.

6 more papers on cholesterol not summarised above

Ordered by strength of evidence, then result direction.

01Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-AnalysisMiao R, et al. · Phytotherapy research : PTR · 2025

Systematic Review · matched via Cholesterol · PubMed record (CORPUS-A)

PMID 40439602 ↗02Efficacy and safety of berberine on the components of metabolic syndrome: a systematic review and meta-analysis of randomized placebo-controlled trialsLiu D, et al. · Frontiers in pharmacology · 2025

Systematic Review · matched via Cholesterol · PubMed record (CORPUS-A)

PMID 40740996 ↗03The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic reviewNie Q, et al. · Journal of translational medicine · 2024

Meta-Analysis · matched via Cholesterol · PubMed record (CORPUS-A)

PMID 38429794 ↗04A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adultsOsadnik T, et al. · Pharmacological research · 2022

Network Meta-Analysis · matched via Cholesterol · PubMed record (CORPUS-A)

PMID 35988871 ↗05Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis

Linked compounds

Browse every linked compound.

These compounds appear in related research or traditional use. Their position is not a recommendation or ranking. Research scores summarise published studies only.

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