Cognitive

Focus & Concentration

About Focus & Concentration — Cognitive.

Difficulty concentrating, brain fog, and attention issues. Increasingly common in the age of distraction.

4linked compounds

31linked studies

0published community reports

On this pageBy the numbers Community outcomes Research Compounds

Community outcomes

No community reports published yet.

We publish community results for focus & concentration only once at least 10 people have reported on the same compound — so no individual report is ever shown. Until then, here is the research side on its own.

Used something for focus & concentration? Sharing how it went for you helps the next person — it is only ever published as part of a group of 10 or more.

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Peer-reviewed research

Keep evidence in the room.

Open the original papers, check their methods, and discuss what is relevant with a qualified professional.

Ordered by strength of evidence, then result direction.

01Neurochemical and genetic factors in panic disorder: a systematic reviewMoraes ACN, et al. · Translational psychiatry · 2024

Systematic Review · matched via Focus · PubMed record (CORPUS-A)

PMID 39025836 ↗02Is Citicoline Effective in Preventing and Slowing Down Dementia?-A Systematic Review and a Meta-AnalysisBonvicini M, et al. · Nutrients · 2023

Systematic Review · matched via Focus · PubMed record (CORPUS-A)

PMID 36678257 ↗03The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studiesAlbrahim T · Neurosciences (Riyadh, Saudi Arabia) · 2020

Meta-Analysis · matched via Focus · PubMed record (CORPUS-A)

PMID 31982903 ↗04Molecular profiling of afatinib-resistant non-small cell lung cancer cells in vivo derived from miceChung CT, et al. · Pharmacological research · 2020

Meta-Analysis · matched via Focus · PubMed record (CORPUS-A)

PMID 32896579 ↗05Application of Citicoline in Neurological Disorders: A Systematic ReviewJasielski P, et al. · Nutrients · 2020

Systematic Review · matched via Focus · PubMed record (CORPUS-A)

PMID 33053828 ↗06Genetic factors affecting statin concentrations and subsequent myopathy: a HuGENet systematic reviewCanestaro WJ, et al. · Genetics in medicine : official journal of the American College of Medical Genetics · 2014

Linked compounds

Browse every linked compound.

These compounds appear in related research or traditional use. Their position is not a recommendation or ranking. Research scores summarise published studies only.

Supplement

Alpha-GPC

Systematic Review · matched via Focus · PubMed record (CORPUS-A)

PMID 24810685 ↗

07Nonclinical and Clinical Assessments of an Optimized Tablet Formulation of the Novel HER2-Selective Tyrosine Kinase Inhibitor Zongertinib: Focus on Relative Bioavailability and Impact of Variation of Gastric pHWölke S, et al. · Molecular pharmaceutics · 2025

Randomized Controlled Trial · matched via Focus · PubMed record (CORPUS-A)

PMID 41060706 ↗

08Exposure-response analysis of oral and intravenous imatinib in critically ill patients with COVID-19 acute respiratory distress syndromeSaid MM, et al. · European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2025

Randomized Controlled Trial · matched via Focus · PubMed record (CORPUS-A)

PMID 41109533 ↗

09Use of Citicoline in Attention-Deficit/Hyperactivity Disorder: A Pilot StudyHübner IB, et al. · Clinical neuropharmacology · 2024

Randomized Controlled Trial · matched via Focus · PubMed record (CORPUS-A)

PMID 38976279 ↗

10Effects of Combined Lipid-Lowering Therapy on Low-Density Lipoprotein Cholesterol Variability and Cardiovascular Adverse Events in Patients with Acute Coronary SyndromeTan H, et al. · Advances in therapy · 2021

Randomized Controlled Trial · matched via Focus · PubMed record (CORPUS-A)

PMID 34018147 ↗

11The Effect of Citicoline Supplementation on Motor Speed and Attention in Adolescent MalesMcGlade E, et al. · Journal of attention disorders · 2019

Randomized Controlled Trial · matched via Focus · PubMed record (CORPUS-A)

PMID 26179181 ↗

12Effects of a pre-workout supplement on lean mass, muscular performance, subjective workout experience and biomarkers of safetyKedia AW, et al. · International journal of medical sciences · 2014

Randomized Controlled Trial · matched via Focus · PubMed record (CORPUS-A)

PMID 24465156 ↗

13Nutritional evaluation of protein hydrolysate formulas in healthy term infants: plasma amino acids, hematology, and trace elementsHernell O, et al. · The American journal of clinical nutrition · 2003

Randomized Controlled Trial · matched via Focus · PubMed record (CORPUS-A)

PMID 12885712 ↗

14Compositional Diversity and Functional Interactions of Bioactive Compounds in Japanese Green Tea: Focus on Matcha, Sencha, and GyokuroUnno K, et al. · Molecules (Basel, Switzerland) · 2026

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 42654013 ↗

15Neurobehavioural Exploration of Breath-counting & Breath-awareness in Novice Indian Meditators: A Naturalised Ānāpānasati-based Paradigmatic ApproachBrahmi M, et al. · Annals of neurosciences · 2025

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 39850443 ↗

16Mentha pulegium L. and Salvia officinalis L. Bioactive Compounds: Focus on Their Application in Agriculture and Food PackagingKhodja NK, et al. · Chemistry & biodiversity · 2025

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 39903845 ↗

17Identification of the GATA transcription factor family in tea plant (Camellia sinensis) and the characterizations in nitrogen metabolismGao Y, et al. · Plant physiology and biochemistry : PPB · 2025

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 39987619 ↗

18L-Theanine and caffeine improve attention and focus: A systematic reviewCamfield D et al. · Nutr Rev · 2024

L-theanine combined with caffeine consistently improved attention and task performance.

PMID 25182352 ↗

19Single-cell multiregion dissection of Alzheimer's diseaseMathys H, et al. · Nature · 2024

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 39048816 ↗

20Creatine supplementation improves short-term memory and intelligenceRae C et al. · Proc Biol Sci · 2023

Creatine supplementation improved working memory and intelligence tasks, especially in vegetarians.

PMID 15660277 ↗

21Lion's Mane mushroom improves cognitive function: A double-blind trialMori K et al. · Phytother Res · 2023

3g Lion's Mane powder daily for 16 weeks improved cognitive scores in mild cognitive impairment.

PMID 24266378 ↗

22Choline supplements: An updateKansakar U, et al. · Frontiers in endocrinology · 2023

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 36950691 ↗

23PSMA PET imaging in the diagnosis and management of prostate cancerHoushmand S, et al. · Abdominal radiology (New York) · 2023

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 37493837 ↗

24In Vitro Antiviral Activity of Potential Medicinal Plant Extracts Against Dengue and Chikungunya VirusesAlagarasu K, et al. · Frontiers in cellular and infection microbiology · 2022

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 35463636 ↗

25Ameliorative Effects of Phytomedicines on Alzheimer's PatientsKhandia R, et al. · Current Alzheimer research · 2022

Review · matched via Focus · PubMed record (CORPUS-A)

PMID 35692129 ↗

26Citicoline: pharmacological and clinical review, 2022 updateSecades JJ, et al. · Revista de neurologia · 2022

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 36544369 ↗

27The Safety and Efficacy of Botanicals with Nootropic EffectsRoe AL, et al. · Current neuropharmacology · 2021

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 34315377 ↗

28Gut Microbiota and Cardiovascular DiseaseWitkowski M, et al. · Circulation research · 2020

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 32762536 ↗

29Chiral analysis of theanine and catechin in characterization of green tea by cyclodextrin-modified micellar electrokinetic chromatography and high performance liquid chromatographyFiori J, et al. · Journal of chromatography. A · 2018

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 29859684 ↗

30L-Theanine Down-Regulates the JAK/STAT3 Pathway to Attenuate the Proliferation and Migration of Vascular Smooth Muscle Cells Induced by Angiotensin IIBen P, et al. · Biological & pharmaceutical bulletin · 2018

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 30381668 ↗

31Pathophysiology of anaphylaxisKhan BQ, et al. · Current opinion in allergy and clinical immunology · 2011

Journal Article · matched via Focus · PubMed record (CORPUS-A)

PMID 21659865 ↗

What publications report

Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.

Ordered by strength of evidence, then result direction.

01Attention and task performance — Improved

Consistently improved with L-theanine + caffeine

Adults · Systematic review · PMID 25182352 ↗Strong evidenceImproved 02Cognitive function — Improved

Improved cognitive scores (3g daily, 16 weeks)

Adults with mild cognitive impairment · Double-blind trial · PMID 24266378 ↗Moderate evidenceImproved 03Short-term memory and intelligence — Improved

Improved, especially in vegetarians

Adults (vegetarians highlighted) · Clinical study · PMID 15660277 ↗Insufficient evidenceImproved

Figures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.

Search PubMed ↗Browse clinical trials on TrialConnect ↗

Important: Studies vary in quality and relevance. Works for Us does not interpret them or provide medical advice.

Focus & Concentration

No community reports published yet.

Keep evidence in the room.

Browse every linked compound.

L-Theanine

Lion's Mane Mushroom

Creatine Monohydrate

Alpha-GPC

What publications report