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About Cognitive Function — Cognitive.
Memory, mental clarity, and overall brain health. Critical for healthy ageing and peak performance.
Audited published research per compound. Drill into a pair for the breakdown.
Bar length counts published studies — green marks studies reporting at least one benefit, slate the other studies (no benefit, unclear or harm); labels read benefit studies / all studies.
◆ marks each compound's research score (0-100): how consistently published studies reported a benefit, weighted by study design. It summarises the research, not how well a compound will work for you.
Compounds with published trial evidence for this condition, ranked by strength of evidence. Each result is put in plain terms and comes from the study itself — open “Exact figures” for the published statistics, or follow the study link to read the paper.
| Compound | Evidence strength | What studies found |
|---|---|---|
| Creatine MonohydrateResearch score 36/100 · Limited | 1 systematic review/meta-analysis + 3 randomised trials — 4 studies | 5/12 outcomes showed benefit
|
We publish community results for cognitive function only once at least 10 people have reported on the same compound — so no individual report is ever shown. Until then, here is the research side on its own.
Used something for cognitive function? Sharing how it went for you helps the next person — it is only ever published as part of a group of 10 or more.
Add your outcomeOpen the original papers, check their methods, and discuss what is relevant with a qualified professional.
Every study behind the numbers above is linked next to its result.
Ordered by strength of evidence, then result direction.
01Ginkgo biloba for cognitive impairment and dementiaWieland LS, et al. · The Cochrane database of systematic reviews · 2026Systematic Review · matched via Cognitive Function · PubMed record (CORPUS-A)
PMID 41641880 ↗02Effects of acute exercise on cognitive function: A meta-review of 30 systematic reviews with meta-analysesChang YK, et al. · Psychological bulletin · 2025Meta-Analysis · matched via Cognitive Function · PubMed record (CORPUS-A)
PMID 39883421 ↗03Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trialsRiepe M, et al. · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2025Meta-Analysis · matched via Cognitive Function · PubMed record (CORPUS-A)
PMID 39895346 ↗04Associations between Diet and Cognitive Function in Stroke Survivors: A Systematic Review and Meta-analysisAmanat S, et al. · Advances in nutrition (Bethesda, Md.) · 2025Systematic Review · matched via Cognitive Function · PubMed record (CORPUS-A)
PMID 40355028 ↗05Creatine Supplementation in Combat Sport Athletes: A Narrative Systematic ReviewAshtary-Larky D, et al. · Journal of dietary supplements · 2025These compounds appear in related research or traditional use. Their position is not a recommendation or ranking. Research scores summarise published studies only.
| Ginkgo BilobaResearch score 29/100 · Mixed/Weak | 1 systematic review/meta-analysis + 1 randomised trial — 2 studies | 4/8 outcomes showed benefit
|
| Vitamin B12Research score 29/100 · Mixed/Weak | 1 systematic review/meta-analysis + 1 randomised trial — 2 studies | 2/3 outcomes showed benefit
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| Lion ManeResearch score 47/100 · Limited | 3 randomised trials — 3 studies | 3/5 outcomes showed benefit
|
Systematic Review · matched via Cognitive Function · PubMed record (CORPUS-A)
Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.
Ordered by strength of evidence, then result direction.
Modest benefit
Dementia patients · Meta-analysis · PMID 28295450 ↗Strong evidenceImproved02Episodic memory — ImprovedImproved with DHA-rich supplementation
Adults with mild memory complaints · Systematic review · PMID 32069340 ↗Strong evidenceImproved03Cognitive function — ImprovedSignificantly improved (3g daily, 16 weeks)
Adults with mild cognitive impairment · Double-blind trial · PMID 17425936 ↗Moderate evidenceImprovedFigures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.