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About Migraine — Physical Health.
Recurrent severe headaches, often with nausea, light sensitivity, and visual disturbances.
We publish community results for migraine only once at least 10 people have reported on the same compound — so no individual report is ever shown. Until then, here is the research side on its own.
Used something for migraine? Sharing how it went for you helps the next person — it is only ever published as part of a group of 10 or more.
Add your outcomeOpen the original papers, check their methods, and discuss what is relevant with a qualified professional.
Ordered by strength of evidence, then result direction.
01Medical Cannabis for the Treatment of Migraine in Adults: A Review of the EvidenceOkusanya BO, et al. · Frontiers in neurology · 2022Systematic Review · matched via Migraine · PubMed record (CORPUS-A)
PMID 35711271 ↗02Care and feeding of the endocannabinoid system: a systematic review of potential clinical interventions that upregulate the endocannabinoid systemMcPartland JM, et al. · PloS one · 2014Systematic Review · matched via Migraine · PubMed record (CORPUS-A)
PMID 24622769 ↗03Vaporized cannabis versus placebo for acute migraine: A randomized, double-blind, placebo-controlled crossover trialSchuster NM, et al. · Headache · 2026Randomized Controlled Trial · matched via Migraine · open-access full text · PubMed record (CORPUS-A)
PMID 41469488 ↗04A Phase 2 Randomized Controlled Trial of the Efficacy and Safety of Cannabidivarin as Add-on Therapy in Participants with Inadequately Controlled Focal SeizuresBrodie MJ, et al. · Cannabis and cannabinoid research · 2021Randomized Controlled Trial · matched via Migraine · PubMed record (CORPUS-A)
PMID 33998885 ↗05The Pharmacology of Cannabinoids in Chronic PainCortez-Resendiz A, et al. · Medical cannabis and cannabinoids · 2025Journal Article · matched via Migraine · PubMed record (CORPUS-A)
PMID 40046175 ↗06These compounds appear in related research or traditional use. Their position is not a recommendation or ranking. Research scores summarise published studies only.
Journal Article · matched via Migraine · PubMed record (CORPUS-A)
Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.
Ordered by strength of evidence, then result direction.
Figures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.