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About Sleep Issues — Mental Health.
Difficulty falling asleep, staying asleep, or poor sleep quality. Insomnia affects ~30% of adults.
Audited published research per compound. Drill into a pair for the breakdown.
Bar length counts published studies — green marks studies reporting at least one benefit, slate the other studies (no benefit, unclear or harm); labels read benefit studies / all studies.
◆ marks each compound's research score (0-100): how consistently published studies reported a benefit, weighted by study design. It summarises the research, not how well a compound will work for you.
Compounds with published trial evidence for this condition, ranked by strength of evidence. Each result is put in plain terms and comes from the study itself — open “Exact figures” for the published statistics, or follow the study link to read the paper.
| Compound | Evidence strength | What studies found |
|---|---|---|
| MelatoninResearch score 58/100 · Moderate | 2 systematic reviews/meta-analyses — 2 studies | 8/9 outcomes showed benefit
|
We publish community results for sleep issues only once at least 10 people have reported on the same compound — so no individual report is ever shown. Until then, here is the research side on its own.
Used something for sleep issues? Sharing how it went for you helps the next person — it is only ever published as part of a group of 10 or more.
Add your outcomeOpen the original papers, check their methods, and discuss what is relevant with a qualified professional.
Every study behind the numbers above is linked next to its result.
Ordered by strength of evidence, then result direction.
01The effects of oral cannabidiol supplementation on blood pressure in adults: a systematic review of randomised controlled trialsRoberts A, et al. · Journal of cannabis research · 2026Systematic Review · matched via Sleep · PubMed record (CORPUS-A)
PMID 42321899 ↗02Dysregulation of melatonin rhythm in Parkinson's and Huntington's disease: a systematic review and meta-analysisSuram RP, et al. · Frontiers in aging neuroscience · 2025Systematic Review · matched via Sleep · PubMed record (CORPUS-A)
PMID 41143249 ↗03Effects of Dietary Supplementation in Patients with Restless Legs Syndrome: A Systematic ReviewGonzález-Parejo P, et al. · Nutrients · 2024Systematic Review · matched via Sleep · open-access full text · PubMed record (CORPUS-A)
PMID 39064758 ↗04Sleep disturbances and female infertility: a systematic reviewLi J, et al. · BMC women's health · 2024Systematic Review · matched via Sleep · PubMed record (CORPUS-A)
PMID 39707272 ↗05The Role of Magnesium in Sleep Health: a Systematic Review of Available LiteratureArab A, et al. · Biological trace element research · 2023Systematic Review · matched via Sleep · PubMed record (CORPUS-A)
PMID 35184264 ↗These compounds appear in related research or traditional use. Their position is not a recommendation or ranking. Research scores summarise published studies only.
Systematic Review · matched via Sleep · PubMed record (CORPUS-A)
Outcome summaries extracted from the linked papers' curated records. Educational, not medical advice.
Ordered by strength of evidence, then result direction.
Reduced by ~7 minutes
Adults with sleep complaints · Systematic review & meta-analysis · PMID 23702256 ↗Strong evidenceReduced02Overall sleep quality — ImprovedImproved
Adults with sleep complaints · Systematic review & meta-analysis · PMID 23702256 ↗Strong evidenceImproved03Subjective sleep quality — ImprovedImproved with 500mg daily for 8 weeks
Elderly with insomnia · Randomised controlled trial · PMID 23853647 ↗Moderate evidenceImproved04Sleep satisfaction — ImprovedImproved satisfaction, reduced night waking (400mg daily, 8 weeks)
Adults with sleep complaints · Double-blind randomised trial · PMID 33799711 ↗Moderate evidenceImprovedFigures are reported as published; study designs and populations vary. Works for Us does not interpret results or provide medical advice.